For me, chills and goosebumps most often signal an active connection to a spirit, either a spirit guide or a soul of a dearly departed, or sometimes, "God."

I wrote this senryu about that experience:

"Goosebump raising surge

kinetic energy says

God present for all"

Note: “present” is a double entendre

I wrote that poem specifically about one memorable experience of hearing a story recounted at an AA meeting about how one night, a man with horrific insomnia and alcoholism, had been planning his family annihilition suicide, and the night he was ready to implement his plan, he fell asleep. https://medium.com/illumination/the-presence-of-god-328581f65545