I believe that one can practice acceptance without ever giving up or letting go. From moment to moment, one can accept the present without accepting permanence and in that way, remain serene without ever giving up on change. If it pleases you to do so, you can read more details of these thoughts here: https://medium.com/promptly-written/spiritual-prompts-for-the-week-of-june-12th-18th-86877724cd6b