Yes I know that TED Talk and it is excellent. I see the lack of connection and the lack of alignment with soul as two sides of the same coin. I did have shakey parent bonds but plenty of other connections and for me that lack of young bonding is not enough to explain my substance issues alone. Another reader stated his view that addiction is caused by lack of connection. Lack of alignment with soul can also be stated as lack of connection with self. Have you seen this 3 minute video? That same reader sent it to me and it's based off much of what Hari talks about. https://youtu.be/_Y51YETlzgU it's really moving.

To pick up in what you said, when one lacks alignment with soul, one lacks what you called lack of connection with Spirit, and to fully tie our thoughts together, lack of self love.